Perfluorocyclobutyl-containing Amphiphilic Block Copolymers Synthesized by RAFT Polymerization
Amphiphilic block copolymers containing hydrophobic perfluorocyclobutyl-based (PFCB) polyacrylate and hydrophilic poly(ethylene glycol) (PEG) segments were prepared via reversible addition-fragmentation chain transfer (RAP-T) polymerization. The PFCB-containing acrylate monomer, p-(2-(p-tolyloxy)perfluorocyclobutoxy)phenyl acrylate, was first synthesized from commercially available compounds in good yields, and this kind of acrylate monomer can be homopolymerized by free radical polymerization or RAFT polymerization. Kinetic study showed the 2,2'-azobis(isobutyronitrile) (AIBN) initiated and cumyl dithiobenzoate (CDB) mediated RAFT polymerization was in a living fashion, as suggested by the fact that the number-average molecular weights (M_n) increased linearly with the conversions of the monomer, while the polydispersity indices kept less than 1.10. The block polymers with narrow molecular weight distributions (M_w/M_n≤1.21) were prepared through RAFT polymerization using PEG monomethyl ether capped with 4-cyanopentanoic acid dithiobenzoate end group as the macro chain transfer agent (mPEG-CTA). The length of the hydrophobic segment can be tuned by the feed ratio of the PFCB-based acrylate monomer and the extending of the polymerization time. The micellization behavior of the block copolymers in aqueous media was investigated by the fluorescence probe technique.
作 者： LI, Yongjun ZHANG, Sen FENG, Chun ZHANG, Yaqin LI, Qingnuan LI, Wenxin HUANG, Xiaoyu 作者单位： LI, Yongjun(Laboratory of Nano-biology and Medicine, Shanghai Institute of Applied Physics, Chinese Academy of Sciences,Shanghai 201800, China;Key Laboratory of Organofluorine Chemistry and Laboratory of Polymer Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China)ZHANG, Sen,FENG, Chun,ZHANG, Yaqin,HUANG, Xiaoyu(Key Laboratory of Organofluorine Chemistry and Laboratory of Polymer Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China)
LI, Qingnuan,LI, Wenxin(Laboratory of Nano-biology and Medicine, Shanghai Institute of Applied Physics, Chinese Academy of Sciences,Shanghai 201800, China)
刊 名： 中国化学（英文版） SCI 英文刊名： CHINESE JOURNAL OF CHEMISTRY 年，卷(期)： 2009 27(11) 分类号： O6 关键词： perfluorocyclobutyl amphiphilic block copolymer RAPT