Mesenchymal Stem Cells and Tooth Engineering
Tooth loss compromises human oral health. Although several prosthetic methods, such as artificial denture and dental implants, are clinical therapies to tooth loss problems, they are thought to have safety and usage time issues. Recently, tooth tissue engineering has attracted more and more attention. Stem cell based tissue engineering is thought to be a promising way to replace the missing tooth. Mesenchymal stem cells (MSCs) are multipotent stem cells which can differentiate into a variety of cell types. The potential MSCs for tooth regeneration mainly include stem cells from human exfoliated deciduous teeth (SHEDs), adult dental pulp stem cells (DPSCs), stem cells from the apical part of the papilla (SCAPs), stem cells from the dental follicle (DFSCs), periodontal ligament stem cells (PDLSCs) and bone marrow derived mesenchymal stem cells (BMSCs). This review outlines the recent progress in the mesenchymal stem cells used in tooth regeneration.
作 者： Li Peng Ling Ye Xue-dong Zhou 作者单位： State Key Laboratory of Oral Disease, Sichuan University, Chengdu, China 刊 名： 国际口腔科学杂志（英文版） 英文刊名： INTERNATIONAL JOURNAL OF ORAL SCIENCE 年，卷(期)： 2009 1(1) 分类号： Q813.1 关键词： mesenchymal stem cell tooth engineering dental pulp stem cell