Syntheses of Nucleoside Derivatives Containing Fmoc- or Trityl-protected Amino Acids
Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids via N,N-dicyclohexyl-carbodiimide(DCC) mediated condensation are described. These reactions offer a mild and convenient method to synthesize aminoacylated nucleoside derivatives.
作 者： GUO Hui ZOU Wu-xin JI Qi MA Yu-xin MENG Ji-Ben 作者单位： Department of Chemistry, Nankai University, Tianjin 300071, P. R. China 刊 名： 高等学校化学研究（英文版） ISTIC SCI 英文刊名： CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 年，卷(期)： 2005 21(4) 分类号： O6 关键词： Nucleoside Amino acid Esterification 2′ 3′-O-Isopropylidene-nucleoside