Offline Controlling of Pseudomonas aeruginosa Resistant to protein Inhibitor Antibiotics Using Combination of EDTA and N
Pseudomonas aeruginosa recognized as opportunistic pathogen causes severe infections for hospitalized patients, survive in and resist many antimicrobial agents like antibiotics and disinfectants. The aim of this study is to evaluate the role of EDTA in improving the sensitivity of resistant P. aeruginosa strains to disinfectants and Na-citrate. The strains used in this study were selected in house from Tanta University hospital, Egypt and tested for the synergistic effect of EDTA with Na-citrate or disinfectant (s). The results showed a significant effect ofEDTA in improving P. aeruginosa sensitivity. In conclusion, we proposed that using EDTA in combination with different sanitization compounds and antimicrobial agentsespecially in hospitals aiming to control the spreading of infections.
作 者： Amro Abd Al Fattah Amara Mohamed Zakaria Hussein 作者单位： Amro Abd Al Fattah Amara(Protein Research Department, Genetic Engineering and Biotechnology Research Institute, Mubarak City for Scientific Research and Technology Applications, Alexandria, Egypt.)Mohamed Zakaria Hussein(Department of Microbiology and Immunology, Faculty of Medicine, Tanat University, Tanta , Egypt.)
刊 名： 微生物学通报 ISTIC PKU 英文刊名： MICROBIOLOGY 年，卷(期)： 2006 33(5) 分类号： Q93 关键词： Antimicrobial Sensitivity Preservative Divalent cations