Effect of helium-neon laser on fast excitatory postsynaptic potential of neurons in the isolated rat superior cervical g
The aim of this study is to further measure the effect of 632.8-nm helium-neon laser on fast excitatory postsynaptic potential(f-EPSP)of postganglionic neurons in isolated rat superior cervical ganglia by means of intracellular recording techniques.The neurons with f-EPSP were irradiated by different power densities(1 - 5 mW/cm2)laser.Irradiated by the 2-mW/cm2 laser,the amplitude of the f-EPSP could augment(P ＜ 0.05,paired t test)and even cause action potential at the end of the first 1 - 2 minutes,the f-EPSP could descend and last for 3 - 8 minutes.But the amplitude of the f-EPSP of neurons irradiated by the 5-mW/cm2 laser could depress for the irradiating periods.The results show that:1)the variation of the amplitude of f-EPSP caused by laser is power density-dependent and time-dependent; 2)there exist the second-order phases in the interaction of the helium-neon laser with neurons.These findings may provide certain evidence in explanation of the mechanisms of clinical helium-neon laser therapy.
作 者： 莫华 何萍 莫宁 作者单位： 莫华(Department of Physics)何萍,莫宁(Department of Pharmacology,Guangxi Medical University,Nanning 530021)
刊 名： 中国光学快报（英文版） ISTIC EI 英文刊名： CHINESE OPTICS LETTERS 年，卷(期)： 2004 2(8) 分类号： O43 关键词：