Synthesis and Biological Activities of Novel Thiophosphoryl Oximates Containing Thiazole and 1,2,3-Triazole Rings
In order to find novel high activity and low toxicity agrochemicals,a series of novel thiophosphoryl oximates containing thiazole and 1,2,3-triazole rings 4 were synthesized by the reactions of 1-{1-[(2-chlorothiazol-5-y1)methyl]-5-methyl-1H-1,2,3-triazol-4-yl}ethanone oxime with various asymmetric thiophosphoryl chlorides.Their structures were confn'med by IR,1H NMR,31P NMR,EI-MS and elemental analyses.The target compounds existed as E-configuration,which was deduced by NMR analysis and by comparison with their pyfidyl analog de-termined by X-ray diffraction.The results of preliminary bioassay indicate that some of title compounds possess moderate insecticidal and fungicidal activities.
作 者： ZHU,Xiaofei SHI,Deqing 作者单位： Key Laboratory of Pesticide and Che mical Biology of Ministry of Education,College of Chemistry,Central China Normal University,Wuhan,Hubei430079,China 刊 名： 中国化学（英文版） SCI 英文刊名： CHINESE JOURNAL OF CHEMISTRY 年，卷(期)： 2009 27(3) 分类号： O6 关键词： thiazole,1,2,3-triazole,thiophosphoryl oximate,biological activity